Last edited by Fern
Wednesday, May 6, 2020 | History

2 edition of Biochemistry of normal and abnormal epidermal differentiation found in the catalog.

Biochemistry of normal and abnormal epidermal differentiation

U.S.-Japan Seminar (1979 Boyne Falls, Mich.)

Biochemistry of normal and abnormal epidermal differentiation

proceedings of the U.S.-Japan Seminar, Boyne Mountain Lodge, Boyne Falls, Michigan, July 29-August 2, 1979

by U.S.-Japan Seminar (1979 Boyne Falls, Mich.)

  • 99 Want to read
  • 3 Currently reading

Published by S. Karger in Basel, New York .
Written in English

    Subjects:
  • Epidermis -- Congresses.,
  • Cell differentiation -- Congresses.,
  • Biochemistry -- Congresses.

  • Edition Notes

    Statementeditors, I.A. Bernstein and Makoto Seiji.
    GenreCongresses.
    SeriesCurrent problems in dermatology -- v. 10.
    ContributionsBernstein, I. A., 1919-, Seiji, Makoto, 1926-, National Science Foundation (U.S.), Nihon Gakujutsu Shinkōkai.
    The Physical Object
    Paginationx, 440 p. :
    Number of Pages440
    ID Numbers
    Open LibraryOL21495864M
    ISBN 10380551915X

    The epidermal growth factor receptor/Erb-B/HER family in normal and malignant breast biology SUZANNE A. ECCLES* The Institute of Cancer Research, Surrey, UK ABSTRACT The EGFR/Erb-B receptor tyrosine kinases each play distinct and complementary roles in normal breast development. The four receptors form both homodimers and heterodimers. Human epidermal lipids: characterization and modulations during differentiation Marilyn A. Lamp, Mary L. Williams, and Peter M. Elias Dermatology Service, Veterans Administration Medical Center, Departments of Dermatology and Pediatrics, University of California School of .

    The pivotal role for Ca 2+ in epidermal differentiation is reflected by a 4-fold increase in extracellular Ca 2+ from basal layer to S. corneum. Moreover, addition of Ca 2+ to keratinocytes in vitro arrests the growth in proliferating cells, while also inducing the expression of differentiation markers like Cited by:   • Background.— Loricrin and involucrin are major precursor proteins to the cornified cell envelope expressed late in epidermal differentiation. Involucrin expression starts in the upper spinous layers in normal human epidermis and precedes loricrin Cited by:

    Boyce, S.T., and Ham, R.G. () Calcium-regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum-free serial culture. J. Invest. Dermatol. 81, 33s–40s. PubMed CrossRef Google ScholarCited by: Clinical Biochemistry is enhanced by numerous case studies, examples, and full color throughout. A Companion Website offers resources for students and instructors, including a fully interactive digital microscope--with a range of cell and tissue images for examination--self-assessment activities, and video podcasts that include interviews with.


Share this book
You might also like
Health in the 1970s

Health in the 1970s

Reading, Wokingham, Aldershot, Basingstoke

Reading, Wokingham, Aldershot, Basingstoke

Society & Health in Guyana

Society & Health in Guyana

Scrolls of love

Scrolls of love

Microeconomics

Microeconomics

Pet Shetland sheepdog

Pet Shetland sheepdog

Jock of the bushveld

Jock of the bushveld

changing role of the general superintendent

changing role of the general superintendent

The beaux merchant

The beaux merchant

North Dakota rules of civil procedure governing procedure in the District Courts.

North Dakota rules of civil procedure governing procedure in the District Courts.

Shattered Innocence

Shattered Innocence

Information and communication technology and the Nigerian public service

Information and communication technology and the Nigerian public service

The demon headmaster

The demon headmaster

Biochemistry of normal and abnormal epidermal differentiation by U.S.-Japan Seminar (1979 Boyne Falls, Mich.) Download PDF EPUB FB2

Biochemistry of normal and abnormal epidermal differentiation: proceedings of the U.S.-Japan seminar, Boyne Mountain Lodge, Boyne Falls, Michigan, July August 2, Biochemistry of normal and abnormal epidermal differentiation: proceedings of the U.S-Japan Seminar, Boyne Mountain Lodge, Boyne Falls, Michigan, July August 2, / editors I.A.

Bernstein and Makoto Seiji S. Karger Basel Australian/Harvard Citation. U.S.-Japan Seminar "Biochemistry of Normal and Abnormal Epidermal Differentiation". The epidermal differentiation complex (EDC) is a gene complex comprising over fifty genes encoding proteins involved in the terminal differentiation and cornification of keratinocytes, the primary cell type of the humans, the complex is located on a Mbp stretch within chromosome 1q The proteins encoded by EDC genes are closely related in terms of function, and.

The mitogen-activated protein kinases (MAPK) and epidermal growth factor receptor (EGFR) are also important. Numerous studies indicate that EGFR and MAPK signaling are required for normal epidermal differentiation, particularly of the IF keratinocyte [2,38–41,52].Cited by: Epidermal Growth Factor Signaling.

An epidermal growth factor or EGF is a type of growth factor that controls the proliferation, differentiation and survival of a cell. It is found in all living organisms. The purpose of EGFs is to protect all living tissue by sending out signals for other cells to multiply or release certain chemicals.

Maintaining this barrier requires continuous cell proliferation and differentiation. Moreover, these processes must be balanced to produce a normal epidermis.

The stem cells of the epidermis reside in specific locations in the basal epidermis, hair follicle and sebaceous glands and these cells are responsible for replenishment of this by: title = "Biochemistry of epidermal stem cells", abstract = "Background: The epidermis is an important protective barrier that is essential for maintenance of life.

Maintaining this barrier requires continuous cell proliferation and by: A Civatte body is a damaged basal keratinocyte that has undergone apoptosis, and consist largely of keratin intermediate filaments, and are almost invariably covered with immunoglobulins, mainly IgM.

Civette bodies are characteristically found in skin lesions of various dermatoses, particularly lichen planus and discoid lupus erythematosus. They may also be found in graft-versus-host disease. In: Bernstein IA, Seiji M (eds) Biochemistry of normal and abnormal epidermal differentiation.

Univ Tokyo Press, Tokyo, pp – Google Scholar Montagna W, Parakkal PF Cited by: Part of the Developments in Molecular and Cellular Biochemistry book series (DMCB, volume 4) Summary Cow and human keratinocytes both contain substrate proteins which are to daltons in size but dissociable in SDS to daltons or by: In the epidermis of skin, a fine balance exists between proliferating progenitor cells and terminally differentiating cells.

We examined the effects of TGF-beta s and retinoic acid (RA) on controlling this balance in normal and malignant human epidermal keratinocytes cultured under conditions where most morphological and biochemical features of epidermis in vivo are retained. Abstract. A model of the human epidermis, EpiDerm, based on neonatal foreskin-derived normal human epidermal keratinocytes (NHEK), has recently been characterized by scientists at the University of Iowa College of Dentistry in terms of stratum corneum (SC) lipids and ultrastructure.

KLF4 is required for normal epidermal differentiation, and it specifically accelerates epidermal barrier formation (7, 56); its enforced expression in basal cells causes squamous dysplasia. As expected for a differentiation-specific transcription factor, KLF4 is induced by the inhibition of JNK.

An FLG siRNA-based approach in normal human epidermal keratinocytes was used to create an organotypic dermo-epidermal skin model in vitro [6].

While keratinocyte differentiation appeared largely normal, loss of keratohyalin granules, impaired lamellar body formation, decreased urocanic acid production, and abnormal diffusion barrier function. CHAPTER 1.

ANATOMY AND PHYSIOLOGY OF THE SKIN 3 or stratum spinosum (Murphy, ). The squamous layer is composed of a variety of cells that differ in shape, structure, and subcellular properties depending on their location. Supra - basal spinous cells, for example, are polyhedral in shape and have a rounded nucleus, whereas cells of the upper Cited by: derlying their pathogenesis and exhibit abnormal keratinocyte differentiation, disrupted barrier function, and/or abnormalities of immunocytes.

Linkage of both AD and psoriasis susceptibility to the epidermal differentiation complex on chromo-some 1q21, which encodes at least 30 proteins in-volved in barrier formation, strongly suggests a. Daniel D. Bikle, in Vitamin D (Fourth Edition), Role of Coregulators. The process of epidermal differentiation is sequential.

As noted earlier 1,25(OH) 2 D and VDR regulate all steps from the control of proliferation in the stratum basale, to the regulation of K1, K10, involucrin, and transglutaminase production in the stratum spinosum, to the regulation of loricrin and filaggrin.

Characteristics of retinol accumulation from serum retinol-binding protein by cultured Sertoli cells Janet L. Shingleton, Michael K. Skinner, and David E. Ong Biochemistry,28 (25), pp – Other articles where Epidermal growth factor is discussed: Stanley Cohen: Cohen termed this substance epidermal growth factor (EGF), and he went on to purify it and completely analyze its chemistry.

He and his coworkers found that EGF influences a great range of developmental events in the body. He also discovered the mechanisms by which EGF is taken into and.

Currently not much is known about the mechanisms that govern epidermal stem cell growth and differentiation. This proposal seeks to understand the fundamental mechanisms of epidermal stem cell self-renewal and differentiation through the study of epigenetic factors, which may yield insights in the development of therapies for epidermal disorders.

Dry Skin and Moisturizers: Chemistry and Function presents new information relating to skin biochemistry and pathological changes seen in various dry skin disorders. The book examines the pharmacology of ingredients in moisturizing preparations, providing a broad overview of formulations as well as detailed information on ing contributions from leading researchers from around.agents that modify epidermal differentiation Epidermal structure, thickness, and keratinocyte turnover rate vary according to the developmental stage and physiological state of the tissue.

Hyaluronan is closely involved in keratinocyte proliferation, migration, and differentiation, and therefore participates in all these regulatory changes. Discover Book Depository's huge selection of P Itin books online.

Free delivery worldwide on over 20 million titles. Biochemistry of Normal and Abnormal Epidermal Differentiation. I. A. Bernstein. 29 Apr P. Itin. 20 Mar Paperback. unavailable. Notify me. Normal and Abnormal Epidermal Differentiation.

P. Itin. 01 Dec